The harsh reality is that not everyone you follow will follow you back. However, because of limits that Twitter places you are going to have to unfollow people so you can actually follow people you follow you. Follow that??
The video below explains in detail how I use JustUnfollow.com – their site gets right down to the people who don’t follow you so you can decide who is worth following. I wonder if I can get into a record book about using the word “follow” or “following”.